Thanks for the A2A.
Yes, you can. Every year, ISRO recruits engineers through their ICRB exam. The criteria for you to be eligible for the written test is that you must get some minimum CGPA in your engineering stream (Minimum 6.5 CGPA). On qualifying the written test, you will be called for an interview.
Keep checking the ISRO official website for latest news
All the best 🙂