Yes. ISRO recruits Computer Science engineering graduates for the post of Scientist/Engineers SC. To qualify, applicants need to write an exam and sit for an interview. Along with Computer Sciences, ISRO also inducts Electronics, Mechanical and Civil engineers through the Central Recruitment (ICRB) portal.
More details about the recruitments and ongoing process can be found in ISROs official recruitment website.
http://www.isro.org/scripts/job.aspx
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Vande Matram.