Yes, getting MS Ramaiah at 4900 rank in COMEDK is possible, but it also depends upon what branch you want to take up.
CSE, ECE and ISE have demands and are harder to get as lower ranked students opt for these, but you can still get MS Ramaiah at that rank. So all the best to you.
And if you are not stuck up on taking only MS Ramaiah then there are other good institutions in bangalore as well such as BMS College of Engineering, BMSIT, PES University, Dayanand Sagar College of Engineering and a few others. But at last, the choice is yours.